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Lyme Disease Symptoms


A bull's-eye rash is a distinctive sign of Lyme disease. However, many who have the disease never saw a rash. The rash may occur long after the initial infection.

The Tick-borne Disease Alliance has a list of other tick-borne diseases and their symptoms.

What if I have Lyme disease?

Diagnosing chronic Lyme disease will require an experienced physician. Recent research shows that those who continue to show symptoms after receiving antibiotic treatments have abnormal proteins in their spinal fluid, reflecting a biological basis for a continuing brain dysfunction or disease.


Because testing for antibodies or the DNA of the bacteria is controversial, doctors may or may not trust the reliability of the variety of tests. Diagnosis is often done by determining the exposure and the symptoms. Symptoms vary from person to person. The disease is commonly called “the great imitator” because the symptoms of chronic Lyme disease or late-stage Lyme disease mimics other diseases.


Some symptoms of Lyme disease include:

  • Fatigue
  • Swollen lymph nodes
  • Fever
  • Headache
  • Muscle pain
  • Bulls-eye rash (caution, large percentage do not have the rash)

 Some late-stage disease symptoms:

  • Stiff neck
  • Joint inflammation
  • Behavior and cognitive changes
  • Bell’s palsy (numbness on one side of the face)
  • Impaired muscle control

The information contained in these topics is not intended nor implied to be a substitute for professional medical advice. It is provided for educational purposes only. You assume full responsibility for how you choose to use this information. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment. Talk with your healthcare provider about any questions you may have regarding a medical condition. Nothing contained in these topics is intended to be used for medical diagnosis or treatment.

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